Keywords: Speckle, Correlation spectroscopy, Dynamical properties, Optical properties. 1. measurement and illumination with a femtosecond laser of variable spectral speckle rheology measurements, Opt. Exp. 22 (2014) 6349- 6361.

Laser speckle rheology (LSR) is a new technique we have developed to measure the mechanical properties of tissue. By illuminating the sample with coherent laser light and calculating the speckle intensity modulations from reflected laser speckle patterns, LSR calculates τ, the decay time constant of intensity decorrelation which is closely associated with tissue mechanical properties.

Variations of optical absorption and reduced scattering coefficients further modulate speckle fluctuations, posing a critical challenge for quantitative evaluation of viscoelasticity. We introduce a novel technology, termed laser speckle micro-rheology (LSM) that offers the unique capability to map the viscoelastic properties of the tissue microenvironment. This innovation will provide important insight into mechano-biology of disease progression. Laser speckle microrheology is used to determine a mechanical property of a biological tissue, namely, an elastic modulus. Speckle frames may be acquired by illuminating a coherent light and effectively measure tissue stiffness. Laser speckle rheology (LSR) offers a new, noncontact optical approach.

Biomedical optics express 5 (3), 817-831, 14 May 2019 temporal resolution for images of blood flow was achieved with laser speckle contrast imaging (LSCI)9–12 by measuring the spatial speckle 7 Sep 2018 Although rheology provides a method to access the product viscosity, it lacks non -contact full-field monitoring. We apply a simple correlation. Keywords: Speckle, Correlation spectroscopy, Dynamical properties, Optical properties. 1. measurement and illumination with a femtosecond laser of variable spectral speckle rheology measurements, Opt. Exp. 22 (2014) 6349- 6361. 22 Jun 2020 Semiconductor laser diodes are widely used as illumination light sources in imaging applications. These lasers are popular because they are low Laser speckle micro-rheology in characterization of biomechanical properties of tissues.

av S Larsson · 2019 · Citerat av 2 — Yanai (1973). Laser speckle methods has their origin in solid mechanics and their first On the rheology of dilative granular media: Bridging solid- and fluid-like

The LSR technology is engineered and configured into several embodiments, including bench-top optical systems, endoscopes for minimally invasive procedures, portable point-of-care devices, and microscopes. 3 Laser Speckle Rheology: Technology Platform LSR is an optical technique that evaluates the viscoelastic properties of biological tissues and biomaterials, without applying an external force, physically contacting the specimen, or using exogenous particles, in a passive, noninvasive approach. 30 35 ,37 46 61 64 Laser speckle [Fig.

We introduce a novel technology, termed laser speckle micro-rheology (LSM) that offers the unique capability to map the viscoelastic properties of the tissue microenvironment. This innovation will provide important insight into mechano-biology of disease progression.

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The self-interference of light rays forms a fluctuating speckle pattern captured by the CMOS sensor. Spatio-temporal correlation analysis of speckle Laser speckle rheology (LSR) is a new technique we have developed to measure the mechanical properties of tissue.
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Laser Speckle Rheology (LSR) offers a novel, non-contact optical approach for evaluating the frequency-dependent viscoelastic properties of hydrogels. In LSR, a coherent laser beam illuminates the specimen and a high-speed camera acquires the time-varying speckle images.

In LSR, a coherent laser beam illuminates the Laser speckle rheology (LSR) offers a new noncontact optical approach. LSR uses an inexpensive laser—similar to a common laser pointer to shine laser light on tissue—plus a camera to image speckle patterns reflected from light-scattering particles in the sample. Abstract We introduce a novel technology, termed laser speckle micro-rheology (LSM) that offers the unique capability to map the viscoelastic properties of the tissue microenvironment.

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Laser Speckle Rheology (LSR) erbjuder en ny, icke-kontakt optisk strategi för utvärdering av de frekvensberoende viskoelastiska egenskaperna hos hydrogeler.

equipped with a diode-pumped solid-state laser (wavelength of 660 nm) with a maximum power of 70 mW. single-, multi-speckle analysis, user defined multi-run scripts, online microrheology analysis and full data access. The consistency and viscosity can be described by fluid rheology and are frequently used as Sammanfattning : Laser Doppler flowmetry (LDF) is virtually the only non-invasive technique, except for other laser speckle based techniques, that position sensing, on line laser diffraction slit width monitor. Monochromator Both the X-ray beam (blue) and the laser beam (red) travel a similar pathway Scattering (XRMS, Speckles). 3. structural data to rheological data.